To represent the hand sign for the fruit that keeps the doctor away, My ASL Dictionary has a cartoon of the legendary Johnny Appleseed Chapman, famous for planting apple orchards across the United States.
A young Johnny Appleseed, a tin cooking pot on his head, shows the ASL hand sign for APPLE. The Knuckle of the X hand twists back and forth on the cheek twice, like the stem of an apple being eaten.